Stock Photo - Smoke billows from Launch Pad 39B as the Space Shuttle Endeavour lifts off into an afternoon sky to begin the STS-108 mission to the International Space Station (ISS). Liftoff occurred at 5:19:28 p.m. (EST), December 5, 2001. Onboard were four STS-108 astronauts and three Expedition Four crewmembers en route to replace a three-person crew aboard the orbital outpost.

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