Stock Photo - using immunohistochemical (ihc) technique, this photomicrograph of a human tissue specimen, revealed some of the cytoarchitectural histopathologic changes associated with a nipah virus infection, and its pathogenic influence upon the vascular elements depicted here, including the formation of a thrombus, and degenerative breakdown of the endothelial layer. infection with nipah virus has been associated with an encephalitis (inflammation of the brain) characterized by fever and drowsiness and more serious central nervous system disease, such as coma, seizures, and inability to maintain breathing.